SB-742457

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5-HT6 receptor antagonist

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Catalog No. A14092

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SB-742457 5mg A14092-5

Regular Price: $90.00

Special Price: $76.50

SB-742457 10mg A14092-10

Regular Price: $150.00

Special Price: $127.50

SB-742457 25mg A14092-25

Regular Price: $300.00

Special Price: $255.00

SB-742457 10mM * 1mL in DMSO A14092-10mM-D

Regular Price: $120.00

Special Price: $102.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SB-742457 is a selective 5-HT6 receptor antagonist with cognition, memory, and learning-enhancing effects.

SB-742457

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Chemical Information

Catalog Num A14092
Actions Antagonist
M. Wt 353.444
Formula C19H19N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 607742-69-8
Synonyms GSK 742457, SB742457, SB 742457, GSK742457, SB-742,457
SMILES code C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4
Chemical Name 3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline

Biological Activity

Description
SB-742457 is a selective 5-HT6 receptor antagonist with cognition, memory, and learning-enhancing effects.
Targets
5-HT6
9.63(pKi)

Solubility

Solubility (25°C) * In vitro DMSO 78 mg/mL (220.68 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (5.65 mM)
In vivo 2% DMSO, 48% PEG300, 2% Tween 80 and 48% water 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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