SCH 442416

A2A Receptor Antagonist

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Catalog No. A12695

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SCH 442416 10mg A12695-10

Regular Price: $120.00

Special Price: $96.00

SCH 442416 25mg A12695-25

Regular Price: $240.00

Special Price: $192.00

SCH 442416 50mg A12695-50

Regular Price: $480.00

Special Price: $384.00

SCH 442416 100mg A12695-100

Regular Price: $900.00

Special Price: $720.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SCH 442416 is a selective adenosine A2A receptor antagonist; binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). Displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM).

SCH 442416

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Chemical Information

Catalog Num A12695
Actions Antagonist
M. Wt 389.42
Formula C20H19N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 316173-57-6
Synonyms SCH442416, SCH-442416
SMILES code COC1=CC=C(C=C1)CCCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5
Chemical Name 2-(2-Furanyl)-7-[3-(4-methoxyphenyl?)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]p?yrimidin-5-amine

Biological Activity

Description
SCH 442416 is a selective adenosine A2A receptor antagonist; binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). Displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM).

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