Fig. 1 · Structure

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Schisandrin B

Cat. No. A11991 CAS 61281-37-6
Schisandrin B is the most abundant dibenzocyclooctadiene isolated from the fruit of Schisandra chinensis (Turcz) Baillon or Wu-Wei-Zi (transliterally meaning "the fruit of five tastes" in Chinese), which is a commonly used tonic herb in Chinese medicine, particularly for the treatment of liver ailments.

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Biological Activity

Target & Activity

Target Activity Value
ATR 7.25 μM

Cellular Effect

Cell Line Activity Value Description Reference
HEK-293T IC50 7.3 μM Inhibition of flag-tagged ATR expressed in HEK293T cells using PHAS-1 as substrate after 20 mins by autoradiography [PMID: 22835870]

Specifications

Manufacturer Adooq Bioscience
CAS Number 61281-37-6
Formula C23H28O6
Molecular Weight 400.465
Synonyms Wuweizisu B; Gamma-Schisandrin
SMILES
CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)OC)OC)OCO3

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO 73 mg/mL (182.29 mM)
Water Insoluble
Ethanol 9 mg/mL (22.47 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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