SGC 707

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PRMT3 Inhibitor

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Catalog No. A15450

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SGC 707 10mg A15450-10

Regular Price: $90.00

Special Price: $76.50

SGC 707 25mg A15450-25

Regular Price: $180.00

Special Price: $153.00

SGC 707 50mg A15450-50

Regular Price: $350.00

Special Price: $297.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SGC 707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets.

SGC 707

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Chemical Information

Catalog Num A15450
Actions Inhibitor
M. Wt 298.3
Formula C16H18N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1687736-54-4
Synonyms SGC707, SGC-707
SMILES code C1CCN(C1)C(=O)CNC(=O)NC2=CC3=C(C=C2)C=NC=C3
Chemical Name N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-urea

Biological Activity

Description
SGC 707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets.
Targets
PRMT3 PRMT3
31 nM53 nM(Kd)

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