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SH-4-54

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Stat inhibitor

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Catalog No. A14249

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SH-4-54 5mg A14249-5

Regular Price: $120.00

Special Price: $108.00

SH-4-54 10mg A14249-10

Regular Price: $200.00

Special Price: $180.00

SH-4-54 25mg A14249-25

Regular Price: $340.00

Special Price: $306.00

SH-4-54 10mM * 1mL in DMSO A14249-10mM-D

Regular Price: $185.00

Special Price: $166.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5.

SH-4-54

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Chemical Information

Catalog Num A14249
Actions Inhibitor
M. Wt 610.59
Formula C29H27F5N2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1456632-40-8
Synonyms SH454
SMILES code CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC=C(C=C3)C(=O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F
Chemical Name 4-[[(4-cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-benzoic acid

Biological Activity

Description
SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5.
Targets
STAT3 STAT5
300 nM(Kd)464 nM(Kd)

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (163.77 mM)
Water <1 mg/mL (<1 mM)
Ethanol 79 mg/mL heating (129.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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