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SM-164

cIAP-2 antagonist

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Catalog No. A15800

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SM-164 5mg A15800-5

Regular Price: $280.00

Special Price: $224.00

SM-164 10mg A15800-10

Regular Price: $500.00

Special Price: $400.00

SM-164 25mg A15800-25

Regular Price: $1,000.00

Special Price: $800.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.

SM-164

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Chemical Information

Catalog Num A15800
Actions Antagonist
M. Wt 1121.42
Formula C62H84N14O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 957135-43-2
Synonyms SM 164, SM164
SMILES code CC(C(=O)NC1CCCCC2CCC(N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)C(C7=CC=CC=C7)NC(=O)C8CCC9N8C(=O)C(CCCC9)NC(=O)C(C)NC)NC
Chemical Name (3S,6R,10aR)-6-((S)-2-(methylamino)propanamido)-N-((R)-(1-(4-(4-(4-(4-((S)-((3S,6S,10aS)-6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamido)(phenyl)methyl)-1H-1,2,3-triazol-1-yl)butyl)phenyl)butyl)-1H-1,2,3-triazol-4-yl)(

Biological Activity

Description
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.

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