Solcitinib (GSK2586184)
Catalog No.: A14405
JAK1 inhibitor
Solcitinib is a Janus kinase 1 (JAK1) inhibitor.
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Biological Activity
| Description | Solcitinib is a Janus kinase 1 (JAK1) inhibitor. | ||
|---|---|---|---|
| Targets |
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Product Information
| Catalog Num | A14405 |
|---|---|
| Formula | C22H23N5O2 |
| Molecular Weight | 389.45 |
| CAS Number | 1206163-45-2 |
| SMILES | CC1(CN(C1)C(=O)C2=CC=C(C=C2)C3=CC=CC4=NC(=NN43)NC(=O)C5CC5)C |
| Synonyms | GSK2586184, GSK 2586184, GSK-2586184, GLPG0778, GLPG 0778, GLPG-0778, G154578 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 27 mg/mL (69.33 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (7.7 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.68 mL | 128.39 mL | 256.77 mL |
| 0.5 mM | 5.14 mL | 25.68 mL | 51.35 mL |
| 1 mM | 2.57 mL | 12.84 mL | 25.68 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
