StemRegenin 1 (SR1)

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AhR antagonist

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Catalog No. A12945

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
StemRegenin 1 (SR1) 10mg A12945-10

Regular Price: $50.00

Special Price: $40.00

StemRegenin 1 (SR1) 25mg A12945-25

Regular Price: $100.00

Special Price: $80.00

StemRegenin 1 (SR1) 50mg A12945-50

Regular Price: $160.00

Special Price: $128.00

StemRegenin 1 (SR1) 100mg A12945-100

Regular Price: $270.00

Special Price: $216.00

StemRegenin 1 (SR1) 10mM * 1mL in DMSO A12945-10mM-D

Regular Price: $87.00

Special Price: $69.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

StemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).

StemRegenin 1 (SR1)

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Chemical Information

Catalog Num A12945
Actions Antagonist
M. Wt 466
Formula C24H23N5OS?HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1227633-49-9
Synonyms SR-1
SMILES code CC(C)N1C=NC2=C1N=C(N=C2NCCC3=CC=C(C=C3)O)C4=CSC5=CC=CC=C54
Chemical Name 4-(2-((2-Benzo[b]thiphen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)ethyl)phenol hydrochloride

Biological Activity

Description
StemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).
Targets
Aryl hydrocarbon receptor (AhR) ()
127 nM

Solubility

Solubility (25°C)* In vitro DMSO 86 mg/mL (200.21 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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