STF 118804

NAMPT inhibitor

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Catalog No. A14072

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
STF 118804 10mg A14072-10
$110.00
STF 118804 25mg A14072-25
$220.00
STF 118804 50mg A14072-50
$380.00
STF 118804 10mM * 1mL in DMSO A14072-10mM-D
$85.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

STF 118804 is a highly specific NAMPT inhibitor that reduces the viability of most B-ALL cell lines with high potency IC50 values in the low nanomolar range and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.

STF 118804

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Chemical Information

Catalog Num A14072
Actions Inhibitor
M. Wt 461.53
Formula C25H23N3O4S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 894187-61-2
Synonyms STF118804, STF-118804
SMILES code CC1=CC=C(C=C1)S(=O)(=O)CC2=C(OC(=N2)C3=CC=C(C=C3)C(=O)NCC4=CN=CC=C4)C
Chemical Name 4-(5-Methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide

Biological Activity

Description
STF 118804 is a highly specific NAMPT inhibitor that reduces the viability of most B-ALL cell lines with high potency IC50 values in the low nanomolar range and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.
Targets
NAMPT

Solubility

Solubility (25°C)* In vitro DMSO 61 mg/mL (132.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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