Target & Activity
| Target | Activity | Value |
|---|---|---|
| Topo II |
Fig. 1 · Structure
Documents & Downloads
Voreloxin Hydrochloride
Cat. No.
A15280
CAS
175519-16-1
Topoisomerase inhibitor
Voreloxin Hcl is a small molecule and a naphthyridine analogue with antineoplastic activity; inhibitor of Topo II.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 175519-16-1 |
| Applications | Topoisomerase inhibitor |
| Formula | C18H20ClN5O4S |
| Molecular Weight | 437.9 |
| Synonyms | SNS-595 Hydrochloride; Vosaroxin Hydrochloride; AG 7352 Hydrochloride |
| SMILES | CNC1CN(CC1OC)C2=NC3=C(C=C2)C(=O)C(=CN3C4=NC=CS4)C(=O)O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
| Solvent | Reported Solubility |
|---|---|
| DMSO | 1 mg/mL (2.28 mM) |
| Water | 1 mg/mL (2.28 mM) |
| Ethanol | Insoluble |
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.