Target & Activity
| Target | Activity | Value |
|---|---|---|
| CDK9/cyc T2 | Ki | 0.626 nM |
| CDK9/CycT1 | Ki | 1.68 nM |
| CDK6/cycD1 | Ki | 2.92 nM |
| CDK4/Cyc D1 | Ki | 3.96 nM |
| CDK1/cycB | Ki | 5.4 nM |
| CDK1/cyc A | Ki | 9.1 nM |
6 targets · Scroll to view more
Fig. 1 · Structure
Documents & Downloads
Voruciclib
Cat. No.
A14392
CAS
1000023-04-0
CDK inhibitor
Voruciclib is a flavone and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1000023-04-0 |
| Applications | CDK inhibitor |
| Formula | C22H19ClF3NO5 |
| Molecular Weight | 469.84 |
| SMILES | CN1CC[C@H]([C@@H]1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=C(C=C(C=C4)C(F)(F)F)Cl)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.