VX-222

Catalog No.: A10980
HCV Protease inhibitor
VX-222 is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection.
Grouped product items
Product Name Price Stock Qty
VX-222 5mg
$90.00
In stock
VX-222 10mg
$160.00
In stock
VX-222 50mg
$450.00
In stock
VX-222 100mg
$750.00
In stock
VX-222 10mM * 1mL in DMSO
$139.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's VX-222 has been cited by 2 publications
  • Wataru Ito, .et al. , Antivir Chem Chemother, 2015, Dec; 24(5-6): 148-154 PMID: 27503576
  • Hui Shen, .et al. , PLoS One., 2013, 8(12): e82299 PMID: 24358168
  • Biological Activity
    Discription VX-222 is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection.
    Targets
    Target Value
    Product Information
    Catalog Num A10980
    Formula C25H35NO4S
    Molecular Weight 445.6
    CAS Number 1026785-59-0
    SMILES CC1CCC(CC1)C(=O)N(C2CCC(CC2)O)C3=C(SC(=C3)C#CC(C)(C)C)C(=O)O
    Synonyms VCH222, VX222
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 76 mg/mL (170.55 mM)
    Water Insoluble
    Ethanol 76 mg/mL (170.55 mM)
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.44 mL 112.21 mL 224.42 mL
    0.5 mM 4.49 mL 22.44 mL 44.88 mL
    1 mM 2.24 mL 11.22 mL 22.44 mL
    5 mM 0.45 mL 2.24 mL 4.49 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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