WZ8040

Catalog No.: A10992
EGFR Inhibitor
WZ8040 is a novel EGFR inhibitors that suppress the growth of EGFR-T790M-containing cell lines and inhibit EGFR phosphorylation.
Grouped product items
Product Name Stock
WZ8040 5mg
WZ8040 10mg
WZ8040 50mg
WZ8040 100mg
WZ8040 10mM * 1mL in DMSO
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Biological Activity
Discription WZ8040 is a novel EGFR inhibitors that suppress the growth of EGFR-T790M-containing cell lines and inhibit EGFR phosphorylation.
Targets
Target Value
Product Information
Catalog Num A10992
Formula C24H25ClN6OS
Molecular Weight 481
CAS Number 1214265-57-2
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)SC4=CC=CC(=C4)NC(=O)C=C)Cl
Synonyms WZ-8040
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 86 mg/mL (178.79 mM)
Water Insoluble
Ethanol 3 mg/mL (6.23 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.79 mL 103.95 mL 207.9 mL
0.5 mM 4.16 mL 20.79 mL 41.58 mL
1 mM 2.08 mL 10.4 mL 20.79 mL
5 mM 0.42 mL 2.08 mL 4.16 mL
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