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CXCR4 antagonist
In Stock
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| Target | Activity | Value |
|---|---|---|
| CXCR4 | EC50 | 0.3 nM |
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| U-87MG ATCC | IC50 | 1.8 nM | Antagonist activity at human CXCR4 expressed in human U87 cells expressing CD4 assessed as inhibition of CXCL12-induced cAMP production pretreated for 15 mins before forskolin challenge by TR-FRET analysis | [PMID: 21105715] |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 55778-02-4 |
| Applications | CXCR4 antagonist |
| Formula | C18H18N4 |
| Molecular Weight | 290.36 |
| Synonyms | WZ 811. |
| SMILES | C1=CC=NC(=C1)NCC2=CC=C(C=C2)CNC3=CC=CC=N3 |
| Solvent | Reported Solubility |
|---|---|
| DMSO | 29 mg/mL (99.88 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
