Fig. 1 · Structure
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1,1′-Ethylidenebis[L-tryptophan]
Eosinophil Activator
1,1′-Ethylidenebis[L-tryptophan] is a known eosinophil activator that enhances the proliferation of eosinophilic leukemia cells. This compound induces the release of eosinophil cationic protein and stimulates T cells to produce interleukin-5 (IL-5). At a dosage of 40 µg/kg, it can cause fascia thickening, mast cell infiltration, and fibrosis in adipose and subcutaneous muscle tissues in murine models. 1,1′-Ethylidenebis[L-tryptophan] is suitable for applications in immunology and inflammation research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 132685-02-0 |
| Applications | Eosinophil Activator |
| Formula | C24H26N4O4 |
| Molecular Weight | 434.49 |
| SMILES | CC(N1C2=CC=CC=C2C(C[C@H](N)C(O)=O)=C1)N3C4=CC=CC=C4C(C[C@H](N)C(O)=O)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.