Fig. 1 · Structure
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1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin
Polychlorinated Dibenzo-p-Dioxin (PCDD) Congener
1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzo-p-dioxin (PCDD) congener, primarily known for its interaction with the aryl hydrocarbon receptor (AhR). This compound is associated with adverse biological effects, including fatty liver degeneration, gastrointestinal hemorrhage, and increased mortality in H/W and line A rats at high doses (10,000 μg/kg). Additionally, 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin can lead to sinusoidal distension and significant peliosis in line B. It serves as a critical tool for studying the toxicological effects of dioxin compounds in environmental and pharmacological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 39227-28-6 |
| Applications | Polychlorinated Dibenzo-p-Dioxin (PCDD) Congener |
| Formula | C12H2Cl6O2 |
| Molecular Weight | 390.86 |
| Synonyms | 1,2,3,4,7,8-HxCDD |
| SMILES | ClC1=C(Cl)C=C2C(OC3=C(Cl)C(Cl)=C(Cl)C(Cl)=C3O2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.