Fig. 1 · Structure
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1,2-Dihydrotanshinone
Abietane Diterpene
1,2-Dihydrotanshinone is an abietane diterpene that targets the pathogenic interaction between (CUG)n-RNA and the splicing factor muscleblind-like 1 (MBNL1). This compound inhibits the formation of the complex associated with myotonic dystrophy type 1, making it a valuable tool for investigating the molecular mechanisms underlying this condition. Its biological activity renders it suitable for research applications focused on neuromuscular disorders and RNA metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 77769-21-2 |
| Applications | Abietane Diterpene |
| Formula | C18H14O3 |
| Molecular Weight | 278.30 |
| Synonyms | 1,2-Dihydrotanshinquinone |
| SMILES | O=C(C1=C2C=CC3=C1CCC=C3C)C(C4=C2OC=C4C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.