1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium (18:2 PS sodium) is a phospholipid compound targeting liposome formation. It plays a crucial role in the construction of vesicles composed of concentric phospholipid bilayer membranes, serving as effective platforms for drug delivery systems, particularly in oncological and antimicrobial applications. This compound facilitates the encapsulation of highly polar water-soluble agents within the internal aqueous space of liposomes, while lipophilic compounds integrate into the lipid bilayer. Its use is especially advantageous for the delivery of antisense oligonucleotides, addressing challenges related to cellular uptake efficiency and systemic stability.
1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine sodium (18:2 PS sodium) is a phospholipid compound targeting liposome formation. It plays a crucial role in the construction of vesicles composed of concentric phospholipid bilayer membranes, serving as effective platforms for drug delivery systems, particularly in oncological and antimicrobial applications. This compound facilitates the encapsulation of highly polar water-soluble agents within the internal aqueous space of liposomes, while lipophilic compounds integrate into the lipid bilayer. Its use is especially advantageous for the delivery of antisense oligonucleotides, addressing challenges related to cellular uptake efficiency and systemic stability.
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