Fig. 1 · Structure
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1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine
PP2A/PTP1B Activator
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine serves as an activator of protein phosphatase 2A (PP2A) and protein tyrosine phosphatase 1B (PTP1B). This phosphatidylethanolamine derivative has been shown to enhance the activities of these phosphatases in malignant pleural mesothelioma cells. Additionally, it induces apoptosis in NCI-H28 malignant pleural mesothelioma cells, making it a valuable reagent for research on cancer signaling pathways and therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 61599-23-3 |
| Applications | PP2A/PTP1B Activator |
| Formula | C37H70NO8P |
| Molecular Weight | 687.93 |
| Synonyms | 16:1 PE |
| SMILES | CCCCCC/C=C\CCCCCCCC(O[C@@H](COP(OCCN)(O)=O)COC(CCCCCCC/C=C\CCCCCC)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.