Fig. 1 · Structure
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1,2-DLPC
LRH-1 Agonist Ligand
1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) serves as a ligand for LRH-1 agonists. This phospholipid is utilized in liposome synthesis and exhibits significant biological activity by promoting lipid catabolism and apoptotic processes in adipocytes via a TNFα-dependent pathway. Additionally, 1,2-DLPC mitigates palmitate-induced insulin resistance in myocytes through PPARα-mediated inflammation, making it valuable for research in metabolic disorders and cellular signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 18194-25-7 |
| Applications | LRH-1 Agonist Ligand |
| Formula | C32H64NO8P |
| Molecular Weight | 621.83 |
| Synonyms | 1,2-Dilauroyl-sn-glycero-3-phosphocholine |
| SMILES | CCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.