Documents & Downloads

1,3,5-Tricaffeoylquinic acid

Angiogenesis Inhibitor

1,3,5-Tricaffeoylquinic acid functions as an angiogenesis inhibitor by targeting key signaling pathways involved in vascular development. It effectively inhibits the phosphorylation of VEGFR2, ERK, PI3K, Akt, and mTOR, essential components of angiogenesis. Additionally, this compound promotes apoptosis in cancer cells by upregulating activated caspase-8, Bax, PARP, and caspase-3/9, while downregulating Bcl-2 levels. Due to its cytotoxic effects on ovarian cancer cells and its ability to inhibit tube formation, 1,3,5-Tricaffeoylquinic acid is valuable for research in ovarian cancer studies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1073897-80-9
Applications	Angiogenesis Inhibitor
Formula	C₃₄H₃₀O₁₅
Molecular Weight	678.59
SMILES	OC1=C(O)C=CC(/C=C/C(O[C@@]2(C[C@H]([C@H](O)[C@H](OC(/C=C/C3=CC(O)=C(O)C=C3)=O)C2)OC(/C=C/C4=CC(O)=C(O)C=C4)=O)C(O)=O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.