Fig. 1 · Structure
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1,3-Dibenzyl-5-fluorouracil
Osteoclastogenesis inhibitor
1,3-Dibenzyl-5-fluorouracil is a selective inhibitor of osteoclastogenesis that targets the RANKL and M-CSF signaling pathways. This compound effectively downregulates the expression of osteoclast markers, making it a valuable tool in the investigation of metabolic bone diseases. Its application in research may provide insights into therapeutic strategies for conditions characterized by excessive osteoclast activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 75500-02-6 |
| Applications | Osteoclastogenesis inhibitor |
| Formula | C18H15FN2O2 |
| Molecular Weight | 310.32 |
| SMILES | C1=CC=C(C=C1)CN2C=C(C(=O)N(C2=O)CC3=CC=CC=C3)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.