Fig. 1 · Structure
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1,4-Dichlorobenzene
Mitogenic/Promotional Carcinogen
1,4-Dichlorobenzene is a non-genotoxic, orally active mitogenic and tumor-promoting agent. This compound has been shown to induce liver tumors in certain murine models and to stimulate the growth of spontaneous precancerous lesions, making it valuable for liver cancer research. It alters key biomarkers, including elevated white blood cell counts and increased levels of serum alanine aminotransferase in exposed populations. Additionally, 1,4-Dichlorobenzene is metabolized to 2,5-dichlorophenol, which can serve as a biomarker for exposure. Its specific hepatotoxic properties make it a significant reagent for studies related to liver pathology and carcinogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 106-46-7 |
| Applications | Mitogenic/Promotional Carcinogen |
| Formula | C6H4Cl2 |
| Molecular Weight | 147.00 |
| SMILES | ClC1=CC=C(Cl)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.