Fig. 1 · Structure
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1,4-DPCA ethyl ester
FIH Inhibitor
1,4-DPCA ethyl ester is an ethyl ester derivative of 1,4-DPCA that functions as a factor inhibiting HIF (FIH) inhibitor. This compound significantly affects cellular hypoxia response pathways by modulating HIF stability and activity. It is primarily utilized in research exploring oxygen-sensing mechanisms and potential therapeutic interventions in hypoxia-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 86443-19-8 |
| Applications | FIH Inhibitor |
| Formula | C15H12N2O3 |
| Molecular Weight | 268.27 |
| SMILES | O=C1C2=C(NC=C1C(OCC)=O)C3=NC=CC=C3C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.