Fig. 1 · Structure
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1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one
Antitumor Agent
1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one is an antitumor agent that exhibits significant antiproliferative activity, with effective doses (ED50) of 57.7 μM and 78.8 μM against 26-L5 and HT-1080 cancer cell lines, respectively. Additionally, this compound has been shown to inhibit melanogenesis in B16 melanoma 4A5 cells, indicating its potential utility in studies related to skin disorders and melanoma treatment. Research involving this compound may contribute to the development of therapeutic strategies targeting cancer and pigmentation disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 332371-82-1 |
| Applications | Antitumor Agent |
| Formula | C19H18O3 |
| Molecular Weight | 294.34 |
| SMILES | O=C(/C=C/C=C/C1=CC=C(O)C=C1)CCC2=CC=C(O)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.