Fig. 1 · Structure
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1-Deazaadenosine
ADA Inhibitor
1-Deazaadenosine is a potent inhibitor of adenosine deaminase (ADA), with a Ki value of 0.66 μM. This compound demonstrates significant anti-cancer activity in vitro, indicating its potential utility as a chemotherapeutic agent for lymphoproliferative disorders. Researchers can leverage 1-Deazaadenosine in studies focused on cancer therapeutics and the modulation of adenosine pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 14432-09-8 |
| Applications | ADA Inhibitor |
| Formula | C11H14N4O4 |
| Molecular Weight | 266.25 |
| SMILES | NC1=C2C(N([C@H]3[C@@H]([C@@H]([C@@H](CO)O3)O)O)C=N2)=NC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.