Fig. 1 · Structure
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1-Dehydrocorticosterone 21-acetate
Drug Derivative
1-Dehydrocorticosterone 21-acetate is an acetylated derivative of corticosterone, notable for its dehydrogenation at the C1 position. This compound serves as a valuable precursor in the synthesis of 21-hydroxypregna-1,4-diene-3,11,20-trione, a metabolite of 1α-hydroxycorticosterone identified in skate species. Its applications extend to biochemical research involving steroid metabolism and the investigation of adrenal hormone derivatives.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 58652-04-3 |
| Applications | Drug Derivative |
| Formula | C23H30O5 |
| Molecular Weight | 386.48 |
| Synonyms | 1-DHC 21-acetate |
| SMILES | [H][C@]1([C@]2(C[C@@H]([C@]3([C@@]([H])(CCC4=CC(C=C[C@@]43C)=O)[C@@]2(CC1)[H])[H])O)C)C(COC(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.