Fig. 1 · Structure
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1-Deoxymannojirimycin hydrochloride
α1,2-mannosidase I Inhibitor
1-Deoxymannojirimycin hydrochloride is an inhibitor of α1,2-mannosidase I, exhibiting an IC50 of 20 μM. This compound functions as a selective class I α1,2-mannosidase inhibitor and serves as a potent N-linked glycosylation inhibitor. It demonstrates antiviral activity against HIV-1 strains and is known to promote the accumulation of high mannose structures. 1-Deoxymannojirimycin hydrochloride is relevant in research applications related to liver cancer and colon cancer studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 73465-43-7 |
| Applications | α1,2-mannosidase I Inhibitor |
| Formula | C6H14ClNO4 |
| Molecular Weight | 199.63 |
| SMILES | O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)NC1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.