Fig. 1 · Structure
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1'-epi Gemcitabine hydrochloride
Isomer
1'-epi Gemcitabine hydrochloride is an isomer of the nucleoside analog gemcitabine hydrochloride, primarily utilized as an experimental control in research settings. This compound exhibits significant biological activity by inhibiting DNA synthesis and repair mechanisms, leading to cellular autophagy and apoptosis. Its applications extend to cancer research, particularly in evaluating the effectiveness of antineoplastic agents and understanding their mechanisms of action.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 122111-05-1 |
| Applications | Isomer |
| Formula | C9H12ClF2N3O4 |
| Molecular Weight | 299.66 |
| Synonyms | 1'-epi LY 188011 hydrochloride |
| SMILES | O[C@H]1C(F)(F)[C@@H](N2C(N=C(N)C=C2)=O)O[C@@H]1CO.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.