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1-Formyl-beta-carboline

Catalog No.: A25939
Akt Inhibitor
1-Formyl-beta-carboline is an alkaloid that functions as an Akt inhibitor, disrupting key signaling pathways. It demonstrates significant inhibitory activity against Newcastle disease virus (NDV), with IC50 values below 10 μM and over 90% inhibition at 20 μM concentration. The compound primarily targets the adsorption and entry phases of the NDV life cycle by directly interacting with the NDV hemagglutinin-neuraminidase (HN) protein. Additionally, 1-Formyl-beta-carboline affects viral entry through modulation of the PI3K/Akt signaling pathway.
1-Formyl-beta-carboline 20127-63-3 Akt Inhibitor
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Size Price Stock Qty
1mg
$20.00
In stock
5mg
$25.00
In stock
10mg
$35.00
In stock
25mg
$55.00
In stock
50mg
$80.00
In stock
100mg
$110.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description1-Formyl-beta-carboline is an alkaloid that functions as an Akt inhibitor, disrupting key signaling pathways. It demonstrates significant inhibitory activity against Newcastle disease virus (NDV), with IC50 values below 10 μM and over 90% inhibition at 20 μM concentration. The compound primarily targets the adsorption and entry phases of the NDV life cycle by directly interacting with the NDV hemagglutinin-neuraminidase (HN) protein. Additionally, 1-Formyl-beta-carboline affects viral entry through modulation of the PI3K/Akt signaling pathway.
Product Information
Catalog NumA25939
FormulaC12H8N2O
Molecular Weight196.21
CAS Number20127-63-3
SMILESC1=CC=C2C(=C1)C3=C(C(=NC=C3)C=O)N2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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PI3K/Akt/mTOR > Akt