Fig. 1 · Structure

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1'-Hydroxy bufuralol

Bufuralol Metabolite

1'-Hydroxy bufuralol is a principal metabolite of Bufuralol, formed through the activity of cytochrome P450 isoenzymes CYP2D1 and CYP2D2. This compound serves as a valuable biomarker for assessing the enzymatic activity of CYP2D1 and CYP2D2. Its identification and quantification are essential in pharmacokinetic studies and drug metabolism research, providing insights into individual variability in drug responses.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 57704-16-2
Applications Bufuralol Metabolite
Formula C16H23NO3
Molecular Weight 277.36
Synonyms Ro 03-7410
SMILES
CC(C1=C2OC(C(CNC(C)(C)C)O)=CC2=CC=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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