Fig. 1 · Structure
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1-Hydroxyrutecarpine
Antiplatelet Activity
1-Hydroxyrutecarpine is a hydroxy-derivative of rutaecarpine known for its antiplatelet activity. This compound demonstrates cytotoxic effects with ED50 values of 3.72 µg/mL for P-388 cells and 7.44 µg/mL for HT-29 cells. It is primarily utilized in research focused on cardiovascular diseases and the mechanisms underlying platelet aggregation. Its potential applications extend to the investigation of novel therapeutic strategies for managing clot-related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 53600-24-1 |
| Applications | Antiplatelet Activity |
| Formula | C18H13N3O2 |
| Molecular Weight | 303.31 |
| Synonyms | 1-Hydroxyrutaecarpine |
| SMILES | O=C1N2C(C(NC3=C4C=CC=C3)=C4CC2)=NC5=C1C=CC=C5O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.