Fig. 1 · Structure

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1-Methyl-2-(4Z,7Z)-4,7-tridecadienyl-4(1H)-quinolone

Cat. No. A49372 CAS 120693-53-0

DGAT Inhibitor

1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone is a diacylglycerol acyltransferase (DGAT) inhibitor, demonstrating an IC50 of 20.1 μM. Additionally, it acts as an angiotensin II receptor blocker with an IC50 of 34.1 μM. This compound exhibits significant anti-Helicobacter pylori activity, with a minimum inhibitory concentration (MIC) of 10 μg/mL, making it valuable for studies investigating lipid metabolism and bacterial infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 120693-53-0
Applications DGAT Inhibitor
Formula C23H31NO
Molecular Weight 337.50
SMILES
CN1C2=CC=CC=C2C(C=C1CCC/C=C\C/C=C\CCCCC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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