Fig. 1 · Structure
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1-Methyl-2-(6Z,9Z)-6,9-pentadecadienyl-4(1H)-quinolone
Angiotensin II Receptor Antagonist
1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone is an antagonist of the angiotensin II receptor with an IC50 of 48.2 μM. This compound, a quinolone alkaloid derived from Evodia rutaecarpa, exhibits significant biological activity relevant to the modulation of cardiovascular functions. It is applicable in research focused on hypertension, heart failure, and related vascular diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 120693-52-9 |
| Applications | Angiotensin II Receptor Antagonist |
| Formula | C25H35NO |
| Molecular Weight | 365.55 |
| SMILES | O=C1C2=CC=CC=C2N(C(CCCCC/C=C\C/C=C\CCCCC)=C1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.