1-Oleoyl-2-acetyl-sn-glycerol is a cell-permeable diacylglycerol (DAG) analog that activates Protein Kinase C (PKC) as its primary target. It is known to induce specific Ca2+ influx through TRPC channels, enhance superoxide production in human neutrophils, and promote the synthesis of phosphatidylinositol 4-phosphate in intact human platelets. Additionally, 1-Oleoyl-2-acetyl-sn-glycerol has been demonstrated to stimulate the proliferation of ascites tumor cells, making it useful for various biochemical and pharmacological studies.
1-Oleoyl-2-acetyl-sn-glycerol is a cell-permeable diacylglycerol (DAG) analog that activates Protein Kinase C (PKC) as its primary target. It is known to induce specific Ca2+ influx through TRPC channels, enhance superoxide production in human neutrophils, and promote the synthesis of phosphatidylinositol 4-phosphate in intact human platelets. Additionally, 1-Oleoyl-2-acetyl-sn-glycerol has been demonstrated to stimulate the proliferation of ascites tumor cells, making it useful for various biochemical and pharmacological studies.
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