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10-Aminocamptothecin

Camptothecin Derivative

10-Aminocamptothecin is a camptothecin derivative that inhibits topoisomerase I, leading to interference with DNA replication and transcription. This compound exhibits potent cytotoxic activity against various cancer cell lines, making it valuable for anticancer research. Additionally, it serves as a useful tool for investigating the mechanisms of DNA damage and repair pathways in cellular models.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	86639-63-6
Applications	Camptothecin Derivative
Formula	C₂₀H₁₇N₃O₄
Molecular Weight	363.37
SMILES	O=C1N2C(C(C(C2)=CC3=C4)=NC3=CC=C4N)=CC5=C1COC([C@]5(O)CC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.