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10m/ZS44

GBM Inhibitor

10m/ZS44 is an effective inhibitor targeting glioblastoma (GBM) with the ability to penetrate the blood-brain barrier. It demonstrates significant inhibition of tumor growth in mouse xenograft models. Additionally, 10m/ZS44 activates the SIRT1/p53-mediated apoptosis pathway, leading to the suppression of U251 cell proliferation, making it a valuable tool for GBM research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3008988-49-3
Applications	GBM Inhibitor
Formula	C₃₁H₃₂N₂O₆
Molecular Weight	528.60
SMILES	COC1=CC(C(/C=C/C2=CC=C(C=C2)C(N3CCN(C34COC4)CC5=CC=CC=C5)=O)=O)=CC(OC)=C1OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.