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10NH2-11F-Camptothecin

ADC Cytoxin

10NH2-11F-Camptothecin is a camptothecin analogue that functions as an antibody-drug conjugate (ADC) cytotoxin. This compound exhibits potent anti-tumor activity by targeting topoisomerase I, ultimately inhibiting DNA replication and promoting cancer cell death. It is utilized in cancer research for the development of innovative therapeutics aimed at improving targeted delivery and efficacy in tumor treatment.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2873460-30-9
Applications	ADC Cytoxin
Formula	C₂₀H₁₆FN₃O₄
Molecular Weight	381.36
SMILES	CC[C@@]1(C2=C(COC1=O)C(N3C(C(C(C3)=CC4=C5)=NC4=CC(F)=C5N)=C2)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.