Fig. 1 · Structure

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(±)11(12)-EET methyl ester

Negative Control

(±)11(12)-EET methyl ester is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET) that serves as a negative control in research applications. This compound does not induce β-arrestin recruitment of the G protein-coupled receptor GPR132 and fails to enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. As a negative control molecule, (±)11(12)-EET methyl ester aids in elucidating the structure-function relationship of 11,12-EET, thereby facilitating investigations into the role of oxygenated fatty acid-GPR132 signaling in hematopoiesis.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 90693-45-1
Applications Negative Control
Formula C21H34O3
Molecular Weight 334.49
Synonyms 11,12-EET methyl ester; (±)11,12-EpETrE methyl ester
SMILES
CCCCC/C=C\C[C@@H]1[C@H](C/C=C\C/C=C\CCCC(OC)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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