Fig. 1 · Structure
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11-cis-Retinal
Drug Derivative
11-cis-Retinal is an oxidized derivative of 11-cis-Retinol that acts as an inverse agonist by binding to opsin in the mammalian visual system, stabilizing the inactive conformation of rhodopsin. This compound is essential for vision and is involved in growth and development processes. Research indicates that 11-cis-Retinal can restore visual function in moths with impaired vision and has demonstrated the ability to recover retinal function in a mouse model of early-age Leber congenital amaurosis type 2 (LCA2) retinal degeneration.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 564-87-4 |
| Applications | Drug Derivative |
| Formula | C20H28O |
| Molecular Weight | 284.44 |
| Synonyms | 11-cis Retinaldehyde; 11-cis Vitamin A aldehyde |
| SMILES | CC(/C=C\C=C(\C=C\C1=C(CCCC(C)1C)C)C)=C\C=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.