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11-Dehydrodexamethasone

11β-HSD Substrate

11-Dehydrodexamethasone is an effective substrate for the enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD) type 1 and type 2. It is primarily utilized to study the enzymatic conversion to Dexamethasone through the reductive activity of 11β-HSD. This compound is valuable in research focusing on steroid metabolism, regulatory mechanisms of glucocorticoids, and their implications in various physiological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	2964-81-0
Applications	11β-HSD Substrate
Formula	C₂₂H₂₇FO₅
Molecular Weight	390.45
SMILES	F[C@@]12[C@](CCC([C@@]2(C=C3)C)=CC3=O)([H])[C@@]4([H])[C@](CC1=O)([C@](O)([C@@H](C4)C)C(CO)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.