Fig. 1 · Structure
Documents & Downloads
11-Deoxyglycyrrhetinic acid sodium
BK Channel Activator
11-Deoxyglycyrrhetinic acid sodium is a BK channel activator, specifically targeting Ca2+/voltage-gated K+ large conductance (BK) channels. This compound demonstrates significant anti-inflammatory properties and effectively activates BK channels derived from rat cerebral artery myocytes, with an EC50 of 53 μM. It is useful in research exploring cardiovascular function and the modulation of inflammatory responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1148013-87-9 |
| Applications | BK Channel Activator |
| Formula | C30H47NaO3 |
| Molecular Weight | 478.68 |
| SMILES | C[C@]12[C@@](CC=C3[C@]2(CC[C@@]4([C@@]3([H])C[C@](C)(CC4)C(O[Na])=O)C)C)([H])[C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])CC1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.