Fig. 1 · Structure
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11-Hydroxytephrosin
NF-kappaB Inhibitor
11-Hydroxytephrosin is a potent inhibitor of NF-kappaB, a transcription factor that regulates genes involved in immune response, apoptosis, tumorigenesis, and tissue differentiation. By modulating NF-kappaB activity, this compound serves as a valuable tool in research focused on inflammatory diseases, cancer biology, and cellular signaling pathways. Its ability to interfere with NF-kappaB signaling may provide insights into therapeutic strategies for conditions associated with dysregulated immune and apoptotic mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 72458-85-6 |
| Applications | NF-kappaB Inhibitor |
| Formula | C23H22O8 |
| Molecular Weight | 426.42 |
| SMILES | O=C1[C@]2(O)[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC(O)=C14 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.