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11-Thiohomoaminopterin

Catalog No.: A93632
Biochemical Reagent
11-Thiohomoaminopterin is a potent biochemical reagent that serves as an analog of 11-thiohomofolic acid. This compound exhibits strong affinity for dihydrofolate reductase, thereby influencing folate metabolism. Its key biological activities make it applicable in cancer research and studies involving antifolate mechanisms in cellular processes.
11-Thiohomoaminopterin 74163-10-3 Biochemical Reagent
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description11-Thiohomoaminopterin is a potent biochemical reagent that serves as an analog of 11-thiohomofolic acid. This compound exhibits strong affinity for dihydrofolate reductase, thereby influencing folate metabolism. Its key biological activities make it applicable in cancer research and studies involving antifolate mechanisms in cellular processes.
Product Information
Catalog NumA93632
FormulaC20H21N7O5S
Molecular Weight471.49
CAS Number74163-10-3
SMILESO=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(SCCC2=NC3=C(N)N=C(N)N=C3N=C2)C=C1)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Others > Biochemical Assay Reagents