Fig. 1 · Structure

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116-9e

DNAJA1/SV40 Inhibitor

116-9e is a potent inhibitor of the DNAJA1 protein, a co-chaperone of Hsp70. This compound effectively disrupts Simian Virus 40 (SV40) replication and DNA synthesis by inhibiting the ATPase activity of tumor antigen (TAg), which in turn impedes TAg-mediated activation of Hsp70. 116-9e is a valuable tool for studying the molecular mechanisms of viral replication and chaperone activity in oncogenic processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 831217-43-7
Applications DNAJA1/SV40 Inhibitor
Formula C31H32N2O5
Molecular Weight 512.60
Synonyms MAL2-11B
SMILES
O=C(CCCCCN1C(C)=C(C(NC1=O)C2=CC=C(C=C2)C3=CC=CC=C3)C(OCC4=CC=CC=C4)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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