11β-HSD1-IN-24 is a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with an IC50 of 0.5 nM. This compound effectively inhibits the conversion of inactive cortisone to active cortisol, making it a valuable tool for research in metabolic diseases, particularly type 2 diabetes. Its high selectivity and potency position it as an important reagent for studying the physiological roles of glucocorticoids in metabolic pathways.
11β-HSD1-IN-24 is a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with an IC50 of 0.5 nM. This compound effectively inhibits the conversion of inactive cortisone to active cortisol, making it a valuable tool for research in metabolic diseases, particularly type 2 diabetes. Its high selectivity and potency position it as an important reagent for studying the physiological roles of glucocorticoids in metabolic pathways.
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