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11β-HSD1-IN-25

Name: 11β-HSD1-IN-25
Brand: Adooq Bioscience
SKU: A57677
Availability: OutOfStock

Cat. No. A57677 CAS 1261266-23-2

11β-HSD1 Inhibitor

11β-HSD1-IN-25 is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). This compound effectively reduces glucocorticoid levels both in vitro and in serum, while also diminishing lipid accumulation in various models. It modulates lipid metabolism through dual mechanisms involving the inhibition of 11β-HSD1 and activation of the AMP-activated protein kinase (AMPK) signaling pathway. 11β-HSD1-IN-25 is suitable for research applications focused on obesity and related metabolic disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1261266-23-2
Applications	11β-HSD1 Inhibitor
Formula	C₂₁H₁₂F₈O
Molecular Weight	432.31
SMILES	O=C1/C(CC/C1=C\C2=C(C(F)(F)F)C=CC=C2F)=C/C3=C(C(F)(F)F)C=CC=C3F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.