11β-HSD1-IN-7

Catalog No.: A68942
11β HSD1 Inhibitor
11β-HSD1-IN-7 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), demonstrating an IC50 value of 1.9 μM in human enzymatic assays. This compound is valuable for investigating the role of 11β-HSD1 in metabolic disorders such as diabetes and age-related cognitive decline. Its selective inhibition of 11β-HSD1 makes it a useful tool for research into therapeutic strategies targeting these conditions.
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Size Price Stock Qty
1g
$20.00
In stock
5g
$60.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description11β-HSD1-IN-7 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), demonstrating an IC50 value of 1.9 μM in human enzymatic assays. This compound is valuable for investigating the role of 11β-HSD1 in metabolic disorders such as diabetes and age-related cognitive decline. Its selective inhibition of 11β-HSD1 makes it a useful tool for research into therapeutic strategies targeting these conditions.
Product Information
Catalog NumA68942
FormulaC14H9F3O
Molecular Weight250.22
CAS Number728-86-9
SMILESO=C(C1=CC=CC=C1)C2=CC=C(C(F)(F)F)C=C2
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