11β-HSD1-IN-9 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with IC50 values of 0.48 µM for human and 1.3 µM for murine isoforms. This compound competes with rat 11β-HSD1, making it a valuable tool for investigating the enzyme's role in metabolic disorders. Applications include studies focused on obesity, hyperglycemia, and cognitive impairments, offering insights into the therapeutic potential of targeting 11β-HSD1 in related diseases.
11β-HSD1-IN-9 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with IC50 values of 0.48 µM for human and 1.3 µM for murine isoforms. This compound competes with rat 11β-HSD1, making it a valuable tool for investigating the enzyme's role in metabolic disorders. Applications include studies focused on obesity, hyperglycemia, and cognitive impairments, offering insights into the therapeutic potential of targeting 11β-HSD1 in related diseases.
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