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12R,13S-Dihydroxyfumitremorgin C

LXR Agonist

12R,13S-Dihydroxyfumitremorgin C is a potent LXRα agonist that activates liver X receptors, which play a critical role in lipid metabolism and cholesterol homeostasis. This compound has been shown to influence gene expression related to lipid regulation, making it valuable for research into metabolic diseases and cardiovascular health. Its agonistic action on LXRα positions it as a useful tool for exploring therapeutic strategies in the context of dyslipidemia and atherosclerosis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	111427-99-7
Applications	LXR Agonist
Formula	C₂₂H₂₅N₃O₅
Molecular Weight	411.45
SMILES	COC1=CC(NC2=C3[C@H](O)[C@]4(O)N(C([C@@](CCC5)([H])N5C4=O)=O)[C@H]2/C=C(C)/C)=C3C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.